Our Team - Principal Investigators

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Stine Falsig Pedersen

Professor Stine F. Pedersen’s primary fields of research are mammalian acid-base homeostasis and associated signaling events in health and disease; structure-function relations, regulatory interactions, physiology and pathophysiology of acid-base transport proteins, with a focus on the Na+/H+ exchanger NHE1 and the Na+,HCO3- cotransporter NBCn1. She is currently at the head of the NHE1 group in the University of Copenhagen, managing 3 postdocs, 4 PhD students, and around 10 masters students and research assistants. Her group studies cellular acid-base homeostasis and associated signaling in normal physiology, cancer, and metabolic disease. Its specific interests are how pH is regulated in each cellular compartment, how it is sensed by cells, and how it in turn regulates cellular functions – as well as structure-function and regulatory interactions of pH regulatory transport proteins.

For more information about her work:
https://www1.bio.ku.dk/english/research/cbp/the-nhe1-group/

Rodolphe Marie

Associate Professor Rodolphe Marie’s primary fields of research are Nanofluidics and Bioimaging; and Fluidics at the micro- and nanoscale to manipulate and image biological particles. In his lab, they focus on experimental nanofluidics for the manipulation and imaging of biologically relevant particles such as macro-molecules, lipid vesicles, metaphase chromosomes and cells. Their goal is to provide new tools for the life sciences based on a combination of micro-/nanofluidics, biophysics, and optical imaging techniques.

For more information about his work:
https://www.healthtech.dtu.dk/forskning/forskningssektioner/section-nanobiophys/group-nanofluidics-and-bioimaging

Albin Sandelin

Professor Albin Gustav Sandelin’s primary fields of research are gene regulation bioinformatics and tag-based expression and promoter analysis. He is currently at the head of the Sandelin lab in the University of Copenhagen, managing 4 postdocs, 6 PhD students and a research technician. The Sandelin lab has a dual focus: Medical transcriptomics and fundamental gene regulation. On the medical side, they work with pancreatic cancer genetics / microenvironment and inflammatory states including inflammatory bowl disease and prenatal programming of disease. They have a long string of discoveries in fundamental gene regulation, including enhancer RNAs and promoter action. The laboratory is both computational and experimental, and many postdocs and PhDs do both. 

For more information about his work:
https://www.sandelinlab.org/

Ute Resch-Genger

Professor Ute Resch-Genger’s primary fields of research are: Fluorescence spectroscopic and microscopic investigations including the relative and absolute measurement of fluorescence quantum yields of liquid and solid, transparent and translucent materials in the UV/VIS/NIR spectrum range (350–1700 nm); Traceable, temperature-dependent and polarisation-dependent measurements of optical properties (absorption, scatter, reflection, luminescence) of chromophore systems; Quantification of functional groups, ligands, and biomolecules on particle surfaces and 2D substrates; and Traceable calibration strategies and standards.

She is currentlly at the head of the Biophotonics division in the Federal Institute for Materials Research and Testing (BAM, Berlin, Germany). The focus of the Biophotonics division's work lies in optical methods for the measurement and characterisation of the interaction of materials and light, for example in applications in materials research, bioanalytics, medicine, environmental chemistry, pharmaceuticals, bioengineering, genetic engineering, agriculture and food technology. The research includes the design, the traceable spectroscopic characterisation and the application of functional organic, inorganic, and hybrid molecular and nanoscale chromophore systems and bioconjugates.

For more information about her work:
https://www.bam.de/Navigation/EN/About-us/Organisation/Organisation-Chart/President/Department-1/Division-12/division12.html

Our Team - Postdocs

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Jamie Auxillos - Albin Sandelin’s lab

Jamie Auxillos has expertise in RNA biology, biotechnology and laboratory automation. Her previous work explored the interactions between sequence elements in the 5’UTR, 3’UTRs on gene expression and their implications on RNA stability. Within the Micrograd project, she is working to apply spatial transcriptomics to cells grown within the microfluidics device to associate changes in gene expression of cells to microenvironmental gradients they were subject to.

Roxane Crouigneau - Stine Pedersen’s lab

Roxane Crouigneau has a very diverse scientific background, from chemistry to cell biology, with expertise in chemical analysis, hydrogels, spheroid and organoid growth, cell encapsulation and cell therapy, microscopy, image analysis, and more generally, in the development of in vitro assays for various applications. In her previous work, she designed and developed a microfluidic system for cell encapsulation for type 1 diabetes, using droplet microfluidics. Within the Micrograd project, she works on the development and optimization of cell growth in the device, and the study of their phenotypic response to microenvironmental spatiotemporal gradients.

Yanfang Li - Rodolphe Marie’s lab

Yanfang Li has a broad scientific background with expertise in advanced material fabrication and their application in drug delivery, tissue engineering and diagnostic biosensor. She has professional knowledge in material science, cell biology, cell-based in vitro assays, bio-analytical techniques, and advanced fluorescence microscopy. With in the Micrograd project, she is working on design and fabricate microfludic devices to reconstructing multifactorial gradients of tumor microenvironment.